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As to early cases, in spondylitis deformans the bone changes may be marked and the clinical symptoms shght, while in the ankylosing spondylitis severe clinical symptoms may precede demonstrable bone and joint changes by a year me or longer. If, as shown solution will not exert a"germicidal" effect on staphylococcus in acid broth in a test tube in five minutes (where the germ is completely submerged), how can it exert a"germicidal" effect upon staphylococcus in the human being where it is not in contact with the germ even for that length of time, and where it has to combat conditions in the human system which are less favorable to the action of bi-chloride, than those which are The following table is from Report of Council on Pharmacy of American GERMICIDAL TESTS DILUTIONS OF THE does not kill staphylococcus in five minutes, how can it in a vaginal douche exert a"germicidal" action when it where is not in contact with the affected part even for that length of time.

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